Lp(a) Antikörper (AA 1823-2013)

Produktnummer ABIN969533

Der Maus Monoklonal Anti-Lp(a)-Antikörper wurde für ELISA, IHC und ICC validiert. Er ist geeignet, Lp(a) in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Lp(a) Antikörper (AA 1823-2013) (ABIN969533)

Target: Lp(a) (Lipoprotein (Lp(a)))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Lp(a) Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: 4H1

Produktdetails anti-Lp(a) Antikörper

Bindungsspezifität: AA 1823-2013

Verwendungszweck: LPA Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human LPA (AA: 1823-2013) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Lp(a) Antikörper (ABIN969533)

Nicholls, Tang, Scoffone, Brennan, Hartiala, Allayee, Hazen: "Lipoprotein(a) levels and long-term cardiovascular risk in the contemporary era of statin therapy." in: Journal of lipid research, Vol. 51, Issue 10, pp. 3055-61, (2010) (PubMed).

Rodger, Le Gal, Carrier, Betancourt, Kahn, Wells, Anderson, Lacut, Chagnon, Solymoss, Crowther, Perrier, White, Vickars, Ramsay, Kovacs: "Serum lipoprotein (a) levels in patients with first unprovoked venous thromboembolism is not associated with subsequent risk of recurrent VTE." in: Thrombosis research, Vol. 126, Issue 3, pp. 222-6, (2010) (PubMed).

Details zu Lp(a)

Target: Lp(a) (Lipoprotein (Lp(a)))

Andere Bezeichnung: LPA

Hintergrund: The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.

Molekulargewicht: 501 kDa

UniProt: P08519