PRTN3 Antikörper
(2 Referenzen)-
- Target Alle PRTN3 Antikörper anzeigen
- PRTN3 (Proteinase 3 (PRTN3))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PRTN3 Antikörper ist unkonjugiert
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Applikation
- ELISA
- Verwendungszweck
- Proteinase 3 Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
- Klon
- 3B4
- Isotyp
- IgG2b
- Top Product
- Discover our top product PRTN3 Primärantikörper
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anti-Proteinase 3 (PRTN3) (AA 71-247) antibody
PRTN3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 88-98) antibodyVerified PRTN3 Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 24-249) antibodyPRTN3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 1-170) antibodyPRTN3 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 228-256), (C-Term) antibodyPRTN3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40945 unconjugated
anti-Proteinase 3 (PRTN3) (AA 1-256) antibodyPRTN3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 1-256) antibodyPRTN3 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 139-248) antibodyPRTN3 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 28-170), (pArg3) antibodyPRTN3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis." in: Blood, Vol. 110, Issue 12, pp. 4086-95, (2007) (PubMed).
: "Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism." in: Clinical and experimental immunology, Vol. 145, Issue 1, pp. 63-70, (2006) (PubMed).
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: "Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis." in: Blood, Vol. 110, Issue 12, pp. 4086-95, (2007) (PubMed).
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- Target
- PRTN3 (Proteinase 3 (PRTN3))
- Andere Bezeichnung
- Proteinase 3 (PRTN3 Produkte)
- Hintergrund
- Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
- Molekulargewicht
- 28 kDa
- Gen-ID
- 5657
- UniProt
- P24158
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