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NK2 Homeobox 5 Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch NK2 Homeobox 5 in ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN969487

Kurzübersicht für NK2 Homeobox 5 Antikörper (ABIN969487)

Target

Alle NK2 Homeobox 5 (NKX2-5) Antikörper anzeigen
NK2 Homeobox 5 (NKX2-5)

Reaktivität

  • 41
  • 20
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 43
  • 7
  • 1
Maus

Klonalität

  • 45
  • 6
Monoklonal

Konjugat

  • 41
  • 3
  • 2
  • 2
  • 2
  • 1
Dieser NK2 Homeobox 5 Antikörper ist unkonjugiert

Applikation

  • 44
  • 28
  • 8
  • 6
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
ELISA

Klon

2E1
  • Verwendungszweck

    NKX2.5 Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human NKX2.5 expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Brewer, Alexandrovich, Mjaatvedt, Shah, Patient, Pizzey: "GATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesis." in: Stem cells and development, Vol. 14, Issue 4, pp. 425-39, (2005) (PubMed).

    Ikeda, Hiroi, Hosoda, Utsunomiya, Matsuo, Ito, Inoue, Sumiyoshi, Takano, Nagai, Komuro: "Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 66, Issue 6, pp. 561-3, (2002) (PubMed).

  • Target

    NK2 Homeobox 5 (NKX2-5)

    Andere Bezeichnung

    NKX2.5

    Hintergrund

    NKX2.5: NK2 transcription factor related, locus 5 (Drosophila), also known as CSX. It is a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

    Molekulargewicht

    35 kDa

    Gen-ID

    1482

    UniProt

    P52952

    Pathways

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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