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EPH Receptor B6 Antikörper

This anti-EPH Receptor B6 antibody (ABIN969479) is a Mouse Monoclonal antibody detecting EPH Receptor B6 in WB, ELISA, IHC. Suitable for Human.
Produktnummer ABIN969479

Kurzübersicht für EPH Receptor B6 Antikörper (ABIN969479)

Target

Alle EPH Receptor B6 (EPHB6) Antikörper anzeigen
EPH Receptor B6 (EPHB6)

Reaktivität

  • 78
  • 44
  • 19
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 74
  • 4
  • 1
  • 1
Maus

Klonalität

  • 75
  • 5
Monoklonal

Konjugat

  • 36
  • 6
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser EPH Receptor B6 Antikörper ist unkonjugiert

Applikation

  • 49
  • 38
  • 28
  • 15
  • 13
  • 11
  • 11
  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon

8E7H12
  • Verwendungszweck

    EphB6 Antibody

    Aufreinigung

    Purified antibody

    Immunogen

    Purified recombinant fragment of EphB6 expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified antibody in PBS containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Ogawa, Wada, Okada, Harada, Nakajima, Pasquale, Tsuyama: "EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases." in: Journal of cell science, Vol. 119, Issue Pt 3, pp. 559-70, (2006) (PubMed).

    Matsuoka, Obama, Kelly, Matsui, Nakamoto: "Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration." in: The Journal of biological chemistry, Vol. 280, Issue 32, pp. 29355-63, (2005) (PubMed).

  • Target

    EPH Receptor B6 (EPHB6)

    Andere Bezeichnung

    EphB6

    Hintergrund

    EPH receptor B6 (EphB6), with 1006-amino acid protein(~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.

    UniProt

    O15197

    Pathways

    RTK Signalweg, Hormone Transport
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