UBE2I Antikörper

Produktnummer ABIN969451

Dieses Maus Monoklonal-Antikörper erkennt spezifisch UBE2I in WB, IHC, ELISA, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human und Affe und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für UBE2I Antikörper (ABIN969451)

Target: UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UBE2I Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: 1B10

Produktdetails anti-UBE2I Antikörper

Verwendungszweck: UBE2I Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human UBE2I expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-UBE2I Antikörper (ABIN969451)

Mohideen, Capili, Bilimoria, Yamada, Bonni, Lima: "A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9." in: Nature structural & molecular biology, Vol. 16, Issue 9, pp. 945-52, (2009) (PubMed).

Kuo, Bentsi-Barnes, Barlow, Bae, Pisarska: "Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene." in: Cellular signalling, Vol. 21, Issue 12, pp. 1935-44, (2009) (PubMed).

Details zu UBE2I

Target: UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))

Andere Bezeichnung: UBE2I

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.

Molekulargewicht: 18 kDa

Gen-ID: 7329

UniProt: P63279

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway