SMAD5 Antikörper
Kurzübersicht für SMAD5 Antikörper (ABIN969404)
Target
Alle SMAD5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- SMAD5 Antibody
-
Aufreinigung
- Ascitic fluid
-
Immunogen
- Purified recombinant fragment of human SMAD5 expressed in E. Coli.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Ascitic fluid containing 0.03 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3927-32, (2008) (PubMed).
: "A crucial role of a high mobility group protein HMGA2 in cardiogenesis." in: Nature cell biology, Vol. 10, Issue 5, pp. 567-74, (2008) (PubMed).
-
: "Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3927-32, (2008) (PubMed).
-
- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
-
Andere Bezeichnung
- SMAD5
-
Hintergrund
- Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo, lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.
-
Molekulargewicht
- 52 kDa
-
UniProt
- Q99717
Target
-