RUNX1 Antikörper

Produktnummer ABIN969390

Dieses Anti-RUNX1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von RUNX1 in WB und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für RUNX1 Antikörper (ABIN969390)

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RUNX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 2B5

Produktdetails anti-RUNX1 Antikörper

Verwendungszweck: RUNX1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Synthesized peptide of human RUNX1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-RUNX1 Antikörper (ABIN969390)

Marshall, Moore, Ohki, Kitabayashi, Patterson, Ornelles: "RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis." in: Journal of virology, Vol. 82, Issue 13, pp. 6395-408, (2008) (PubMed).

Ichikawa, Goyama, Asai, Kawazu, Nakagawa, Takeshita, Chiba, Ogawa, Kurokawa: "AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4402-8, (2008) (PubMed).

Details zu RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Andere Bezeichnung: RUNX1

Hintergrund: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

Molekulargewicht: 55 kDa

Gen-ID: 861

UniProt: Q01196