RUNX1 Antikörper

Produktnummer ABIN969389

Der Maus Monoklonal Anti-RUNX1-Antikörper wurde für WB, ELISA und ICC validiert. Er ist geeignet, RUNX1 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für RUNX1 Antikörper (ABIN969389)

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RUNX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Klon: 5A1

Produktdetails anti-RUNX1 Antikörper

Verwendungszweck: RUNX1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Synthesized peptide of human RUNX1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-RUNX1 Antikörper (ABIN969389)

Zharlyganova, Harada, Harada, Shinkarev, Zhumadilov, Zhunusova, Tchaizhunusova, Apsalikov, Kemaikin, Zhumadilov, Kawano, Kimura, Hoshi: "High frequency of AML1/RUNX1 point mutations in radiation-associated myelodysplastic syndrome around Semipalatinsk nuclear test site." in: Journal of radiation research, Vol. 49, Issue 5, pp. 549-55, (2008) (PubMed).

Details zu RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Andere Bezeichnung: RUNX1

Hintergrund: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

Molekulargewicht: 55 kDa

Gen-ID: 861

UniProt: Q01196