MST1R Antikörper (AA 210-320)

Produktnummer ABIN969384

Produktdetails anti-MST1R Antikörper

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Bindungsspezifität: AA 210-320

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MST1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: RON Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human RON (aa210-320) expressed in E. Coli.

Klon: 1B5A9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MST1R Antikörper (ABIN969384)

Zhang, Yao, Wang: "Activation of RON differentially regulates claudin expression and localization: role of claudin-1 in RON-mediated epithelial cell motility." in: Carcinogenesis, Vol. 29, Issue 3, pp. 552-9, (2008) (PubMed).

Lee, Chen, Chow, Su, Lin, Guo: "Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 6, pp. 2222-8, (2005) (PubMed).

Mallakin, Kutcher, McDowell, Kong, Schuster, Lentsch, Aronow, Leikauf, Waltz: "Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury." in: American journal of respiratory cell and molecular biology, Vol. 34, Issue 1, pp. 15-27, (2005) (PubMed).

Details zu MST1R

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Andere Bezeichnung: RON (MST1R Produkte)

Hintergrund: RON (MST1R): macrophage stimulating 1 receptor (c-met-related tyrosine kinase). RON is a receptor tyrosine kinase that is translated as a single polypeptide and then proteolytically cleaved to yield a mature heterodimer consisting of an extracellular 35 kDa a chain disulfide-linked to a membrane-spanning 150 kDa

Molekulargewicht: 152 kDa

Gen-ID: 4486

UniProt: Q04912

Pathways: RTK Signalweg