RBP4 Antikörper

Produktnummer ABIN969380

Der Maus Monoklonal Anti-RBP4-Antikörper wurde für ELISA, IHC, ICC und FACS validiert. Er ist geeignet, RBP4 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für RBP4 Antikörper (ABIN969380)

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RBP4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: 4C2

Produktdetails anti-RBP4 Antikörper

Verwendungszweck: RBP4 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human RBP expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-RBP4 Antikörper (ABIN969380)

van Hoek, Dehghan, Zillikens, Hofman, Witteman, Sijbrands: "An RBP4 promoter polymorphism increases risk of type 2 diabetes." in: Diabetologia, Vol. 51, Issue 8, pp. 1423-8, (2008) (PubMed).

Choi, Kwak, Youn, Lim, Park, Lee, Lee, Cho, Lee, Kim, Park, Jang: "High plasma retinol binding protein-4 and low plasma adiponectin concentrations are associated with severity of glucose intolerance in women with previous gestational diabetes mellitus." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 8, pp. 3142-8, (2008) (PubMed).

Details zu RBP4

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Andere Bezeichnung: RBP4

Hintergrund: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. (provided by RefSeq)

Molekulargewicht: 23 kDa

UniProt: P02753

Pathways: Regulatorische RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response