PODXL Antikörper

Produktnummer ABIN969356

Der Maus Monoklonal Anti-PODXL-Antikörper wurde für WB, IHC, ELISA und FACS validiert. Er ist geeignet, PODXL in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für PODXL Antikörper (ABIN969356)

Target: PODXL (Podocalyxin-Like (PODXL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PODXL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Klon: 5F5

Produktdetails anti-PODXL Antikörper

Verwendungszweck: PODXL Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human PODXL expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-PODXL Antikörper (ABIN969356)

Thomas, Schnaar, Konstantopoulos: "Podocalyxin-like protein is an E-/L-selectin ligand on colon carcinoma cells: comparative biochemical properties of selectin ligands in host and tumor cells." in: American journal of physiology. Cell physiology, Vol. 296, Issue 3, pp. C505-13, (2009) (PubMed).

Details zu PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Andere Bezeichnung: PODXL

Hintergrund: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. (provided by RefSeq)Tissue specificity: Glomerular epithelium cell (podocyte)

Molekulargewicht: 49 kDa

UniProt: O00592

Pathways: Tube Formation