NAMPT Antikörper (AA 338-479)

Produktnummer ABIN969344

Der Maus Monoklonal Anti-NAMPT-Antikörper wurde für ELISA validiert. Er ist geeignet, NAMPT in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für NAMPT Antikörper (AA 338-479) (ABIN969344)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NAMPT Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 1D3A12

Produktdetails anti-NAMPT Antikörper

Bindungsspezifität: AA 338-479

Verwendungszweck: PBEF1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-NAMPT Antikörper (ABIN969344)

Rongvaux, Shea, Mulks, Gigot, Urbain, Leo, Andris: "Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis." in: European journal of immunology, Vol. 32, Issue 11, pp. 3225-34, (2003) (PubMed).

Details zu NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Andere Bezeichnung: PBEF1

Hintergrund: PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

UniProt: P43490