PARL Antikörper (AA 112-167)
(2 Referenzen)Kurzübersicht für PARL Antikörper (AA 112-167) (ABIN969340)
Target
Alle PARL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 112-167
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Verwendungszweck
- PARL Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.
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Isotyp
- IgG2b
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anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibody
PARL Reaktivität: Human, Maus, Ratte, Hund, Pferd, Schwein, Kaninchen, Rind (Kuh), Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibodyPARL Reaktivität: Human, Maus, Ratte, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 1-170) antibodyPARL Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 97-146) antibodyPARL Reaktivität: Human, Maus, Ratte, Hund, Pferd, Schwein, Kaninchen, Fledermaus, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 1-170) antibodyPARL Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (AA 2-100) antibodyPARL Reaktivität: Human ELISA Wirt: Maus Monoclonal 4F4 unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibodyPARL Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Presenilin Associated, Rhomboid-Like (PARL) (N-Term) antibodyPARL Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Mitochondrial membrane remodelling regulated by a conserved rhomboid protease." in: Nature, Vol. 423, Issue 6939, pp. 537-41, (2003) (PubMed).
: "PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2." in: Journal of Alzheimer's disease : JAD, Vol. 3, Issue 2, pp. 181-190, (2002) (PubMed).
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: "Mitochondrial membrane remodelling regulated by a conserved rhomboid protease." in: Nature, Vol. 423, Issue 6939, pp. 537-41, (2003) (PubMed).
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- PARL (Presenilin Associated, Rhomboid-Like (PARL))
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Andere Bezeichnung
- PARL
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Hintergrund
- PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Gen-ID
- 55486
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UniProt
- Q9H300
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Pathways
- Autophagie
Target
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