MYOD1
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
1A7
unconjugated
Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Dacwag, Bedford, Sif, Imbalzano: "Distinct protein arginine methyltransferases promote ATP-dependent chromatin remodeling function at different stages of skeletal muscle differentiation." in: Molecular and cellular biology, Vol. 29, Issue 7, pp. 1909-21, (2009) (PubMed).
Yamamoto, Watt, Schmidt, Kuscuoglu, Miesfeld, Goldhamer: "Cloning and characterization of a novel MyoD enhancer-binding factor." in: Mechanisms of development, Vol. 124, Issue 9-10, pp. 715-28, (2007) (PubMed).
Mal: "Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation." in: The EMBO journal, Vol. 25, Issue 14, pp. 3323-34, (2006) (PubMed).
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.