MSI1 Antikörper

Produktnummer ABIN969294

Dieses Anti-MSI1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MSI1 in WB, ELISA und FACS. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für MSI1 Antikörper (ABIN969294)

Target: MSI1 (Musashi Homolog 1 (Drosophila) (MSI1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MSI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon: 2A12

Produktdetails anti-MSI1 Antikörper

Verwendungszweck: MSI1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human MSI1 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MSI1 Antikörper (ABIN969294)

Sureban, May, George, Dieckgraefe, McLeod, Ramalingam, Bishnupuri, Natarajan, Anant, Houchen: "Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo." in: Gastroenterology, Vol. 134, Issue 5, pp. 1448-58, (2008) (PubMed).

Details zu MSI1

Target: MSI1 (Musashi Homolog 1 (Drosophila) (MSI1))

Andere Bezeichnung: MSI1

Hintergrund: This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas.Musashi-1 is frequently used as a marker for proliferating neural precursor cells, it is also expressed in epithelial stem cells including intestinal and mammary gland stem cells.Tissue specificity: Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.

Molekulargewicht: 39 kDa

UniProt: O43347

Pathways: Stem Cell Maintenance