MERTK Antikörper

Produktnummer ABIN969283

Produktdetails anti-MERTK Antikörper

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MERTK Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: MER Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of MER expressed in E. Coli.

Klon: 7E5G1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MERTK Antikörper (ABIN969283)

McGough, Cummings: "Coeliac disease: a diverse clinical syndrome caused by intolerance of wheat, barley and rye." in: The Proceedings of the Nutrition Society, Vol. 64, Issue 4, pp. 434-50, (2005) (PubMed).

Allouache, Gawande, Tubiana-Hulin, Tubiana-Mathieu, Piperno-Neumann, Mefti, Bozec, Genot: "First-line therapy with gemcitabine and paclitaxel in locally, recurrent or metastatic breast cancer: a phase II study." in: BMC cancer, Vol. 5, pp. 151, (2005) (PubMed).

Seguineau, Soudant, Moal, Delaporte, Miner, Quéré, Samain: "Techniques for delivery of arachidonic acid to Pacific oyster, Crassostrea gigas, spat." in: Lipids, Vol. 40, Issue 9, pp. 931-9, (2005) (PubMed).

Details zu MERTK

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Andere Bezeichnung: MER (MERTK Produkte)

Hintergrund: MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

UniProt: Q12866

Pathways: RTK Signalweg