MDM4-binding Protein Antikörper

Produktnummer ABIN969282

Dieses Anti-MDM4-binding Protein-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MDM4-binding Protein in ELISA, IHC und ICC. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für MDM4-binding Protein Antikörper (ABIN969282)

Target: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MDM4-binding Protein Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Klon: 2D10F4

Produktdetails anti-MDM4-binding Protein Antikörper

Verwendungszweck: MDM4 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human MDM4 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MDM4-binding Protein Antikörper (ABIN969282)

Pan, Chen: "Modification of MDMX by sumoylation." in: Biochemical and biophysical research communications, Vol. 332, Issue 3, pp. 702-9, (2005) (PubMed).

Wunderlich, Ghosh, Weghorst, Berberich: "MdmX represses E2F1 transactivation." in: Cell cycle (Georgetown, Tex.), Vol. 3, Issue 4, pp. 472-8, (2004) (PubMed).

Details zu MDM4-binding Protein

Target: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Andere Bezeichnung: MDM4

Hintergrund: MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.

Molekulargewicht: 55 kDa

Gen-ID: 4194

UniProt: O15151

Pathways: Zellzyklus