MCM2 Antikörper
(2 Referenzen)Kurzübersicht für MCM2 Antikörper (ABIN969281)
Target
Alle MCM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- MCM2 Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human MCM2 expressed in E. Coli.
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Isotyp
- IgG1
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anti-Minichromosome Maintenance Complex Component 2 (MCM2) antibody
MCM2 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 2B3 unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) antibodyMCM2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 805-904) antibodyMCM2 Reaktivität: Human WB, IF, ELISA, IP Wirt: Maus Monoclonal 6A8 unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 884-904) antibodyMCM2 Reaktivität: Maus, Ratte WB, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 360-700) antibodyMCM2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (N-Term) antibodyMCM2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 889-904), (C-Term) antibodyMCM2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 649-677) antibodyMCM2 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 473-679) antibodyMCM2 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 2-904) antibodyMCM2 Reaktivität: Human WB, IHC, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry." in: Molecular cell, Vol. 35, Issue 2, pp. 206-16, (2009) (PubMed).
: "MCM 2 Expression in Basal Cell Carcinomas and Trichoepitheliomas." in: Journal of cutaneous pathology, Vol. 36, Issue 10, pp. 1121-2, (2009) (PubMed).
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: "Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry." in: Molecular cell, Vol. 35, Issue 2, pp. 206-16, (2009) (PubMed).
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- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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Andere Bezeichnung
- MCM2
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Hintergrund
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
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Molekulargewicht
- 125 kDa
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Gen-ID
- 4171
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UniProt
- P49736
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Pathways
- DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
Target
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