MAP3K2 Antikörper

Produktnummer ABIN969272

Der Maus Monoklonal Anti-MAP3K2-Antikörper wurde für ELISA und ICC validiert. Er ist geeignet, MAP3K2 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für MAP3K2 Antikörper (ABIN969272)

Target: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAP3K2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC)

Klon: 4B4

Produktdetails anti-MAP3K2 Antikörper

Verwendungszweck: MAP3K2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human MAP3K2 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MAP3K2 Antikörper (ABIN969272)

Kurada, Li, Mulherkar, Subramanian, Prasad, Prabhakar: "MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13533-41, (2009) (PubMed).

Cazares, Troyer, Mendrinos, Lance, Nyalwidhe, Beydoun, Clements, Drake, Semmes: "Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 17, pp. 5541-51, (2009) (PubMed).

Details zu MAP3K2

Target: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Andere Bezeichnung: MAP3K2

Hintergrund: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Molekulargewicht: 70 kDa

UniProt: Q9Y2U5

Pathways: MAPK Signalweg