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LSD1 Antikörper

KDM1A Reaktivität: Human, Maus, Affe WB, ELISA, IHC Wirt: Maus Monoclonal 1B2E5 unconjugated
Produktnummer ABIN969264
  • Target Alle LSD1 (KDM1A) Antikörper anzeigen
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    Reaktivität
    • 74
    • 36
    • 29
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Affe
    Wirt
    • 58
    • 14
    • 1
    Maus
    Klonalität
    • 58
    • 16
    Monoklonal
    Konjugat
    • 54
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LSD1 Antikörper ist unkonjugiert
    Applikation
    • 66
    • 34
    • 25
    • 21
    • 17
    • 13
    • 13
    • 10
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Verwendungszweck
    LSD1/AOF2 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human LSD1 expressed in E. Coli.
    Klon
    1B2E5
    Isotyp
    IgG1
    Top Product
    Discover our top product KDM1A Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shi, Matson, Lan, Iwase, Baba, Shi: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).

    Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).

  • Target
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    Andere Bezeichnung
    LSD1/AOF2 (KDM1A Produkte)
    Hintergrund
    The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
    Molekulargewicht
    93 kDa
    UniProt
    O60341
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effekt
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