Zitiert in 2+ Publikationen.
Der Maus Monoklonal anti-Lp(a) Antikörper (Klon 8F6A9) (ABIN969261) detektiert spezifisch Lp(a) in ELISA und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Lp(a)
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Ranga, Kalra, Tandon, Gambhir, Mehrotra: "Effect of aspirin on lipoprotein(a) in patients with ischemic stroke." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 16, Issue 5, pp. 220-4, (2007) (PubMed).
Catalano, Cortelazzo, Yilmaz, Perilli, Carzaniga, Emanuele: "The LPA gene C93T polymorphism influences plasma lipoprotein(a) levels and is independently associated with susceptibility to peripheral arterial disease." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 387, Issue 1-2, pp. 109-12, (2007) (PubMed).
Target
Lp(a)
(Lipoprotein (Lp(a)))
Andere Bezeichnung
LPA
Hintergrund
LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation.