Zitiert in 2+ Publikationen.
Der Maus Monoklonal anti-KLHL21 Antikörper (Klon 2H4) (ABIN969246) detektiert spezifisch KLHL21 in ELISA und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
KLHL21
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
Cy7
Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Maerki, Olma, Staubli, Steigemann, Gerlich, Quadroni, Sumara, Peter: "The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 791-800, (2009) (PubMed).
Otsuki, Ota, Nishikawa, Hayashi, Suzuki, Yamamoto, Wakamatsu, Kimura, Sakamoto, Hatano, Kawai, Ishii, Saito, Kojima, Sugiyama, Ono, Okano, Yoshikawa, Aotsuka, Sasaki, Hattori, Okumura, Nagai, Sugano et al.: "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. ..." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 12, Issue 2, pp. 117-26, (2005) (PubMed).
Target
KLHL21
(Kelch-Like 21 (KLHL21))
Andere Bezeichnung
KLHL21
Hintergrund
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.