KLHL12 Antikörper
Kurzübersicht für KLHL12 Antikörper (ABIN969244)
Target
Alle KLHL12 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- KLHL12 Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human KLHL12 expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
- ELISA: 1/10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Ubiquitin-dependent regulation of COPII coat size and function." in: Nature, Vol. 482, Issue 7386, pp. 495-500, (2012) (PubMed).
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: "Ubiquitin-dependent regulation of COPII coat size and function." in: Nature, Vol. 482, Issue 7386, pp. 495-500, (2012) (PubMed).
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- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
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Andere Bezeichnung
- KLHL12
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Hintergrund
- Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
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Molekulargewicht
- 63 kDa
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Gen-ID
- 59349
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UniProt
- Q53G59
Target
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