KLHL12 Antikörper
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- Target Alle KLHL12 Antikörper anzeigen
- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KLHL12 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- kelch-like 12(Drosophila)
- Isotyp
- IgG
- Top Product
- Discover our top product KLHL12 Primärantikörper
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anti-Kelch-Like 12 (Drosophila) (KLHL12) (AA 1-220) antibody
KLHL12 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (AA 376-404), (C-Term) antibodyKLHL12 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB37184 unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) antibodyKLHL12 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2G2 unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (N-Term) antibodyKLHL12 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Meerschweinchen, Schwein, Fledermaus, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Kelch-Like 12 (Drosophila) (KLHL12) (AA 81-341) antibodyKLHL12 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
- Andere Bezeichnung
- KLHL12 (KLHL12 Produkte)
- Synonyme
- zgc:92570 antikoerper, wu:fi60g03 antikoerper, C3ip1 antikoerper, C3IP1 antikoerper, DKIR antikoerper, hDKIR antikoerper, Ski2 like RNA helicase antikoerper, kelch like family member 12 L homeolog antikoerper, kelch like family member 12 antikoerper, kelch-like family member 12 antikoerper, kelch-like 12 antikoerper, SKIV2L antikoerper, klhl12.L antikoerper, KLHL12 antikoerper, klhl12 antikoerper, Klhl12 antikoerper
- Hintergrund
- Synonyms:C3IP1 Background:Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem(ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31(SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3. The BCR(KLHL12) complex also mediates polyubiquitination of DRD4, without leading to degradation of DRD4.
- Molekulargewicht
- 53-56 kDa, 63-67 kDa
- Gen-ID
- 59349
- UniProt
- Q53G59
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