Ki-67 Antikörper (AA 3118-3256)

Produktnummer ABIN969233

Der Maus Monoklonal Anti-Ki-67-Antikörper wurde für ELISA validiert. Er ist geeignet, Ki-67 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Ki-67 Antikörper (AA 3118-3256) (ABIN969233)

Target: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ki-67 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 9C12B2

Produktdetails anti-Ki-67 Antikörper

Bindungsspezifität: AA 3118-3256

Verwendungszweck: Ki67 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of Ki167 (aa3118-3256) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Ki-67 Antikörper (ABIN969233)

Uzüm, Ataoğlu: "Histopathological parameters with Ki-67 and bcl-2 in the prognosis of meningiomas according to WHO 2000 classification." in: Tumori, Vol. 94, Issue 3, pp. 389-97, (2008) (PubMed).

Kasprzak, Adamek, Biczysko, Seidel, Przybyszewska, Olejniczak, Juszczyk, Zabel: "Intracellular expression of the proliferative marker Ki-67 and viral proteins (NS3, NS5A and C) in chronic, long lasting hepatitis C virus (HCV) infection." in: Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society, Vol. 45, Issue 4, pp. 357-66, (2007) (PubMed).

Details zu Ki-67

Target: Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

Andere Bezeichnung: Ki67

Hintergrund: Ki67: antigen identified by monoclonal antibody Ki-67. Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

Molekulargewicht: 358 kDa

Gen-ID: 4288

UniProt: P46013

Pathways: Glycosaminoglycan Metabolic Process