IL-2 Antikörper
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- Target Alle IL-2 (IL2) Antikörper anzeigen
- IL-2 (IL2) (Interleukin 2 (IL2))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser IL-2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of IL2 expressed in E. coli.
- Klon
- 8D5
- Isotyp
- IgG1
- Top Product
- Discover our top product IL2 Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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TGF-beta inhibits IL-2 production and promotes cell cycle arrest in TCR-activated effector/memory T cells in the presence of sustained TCR signal transduction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1490-8, (2008) (PubMed).
: "Regulation of IL-2 expression by transcription factor BACH2 in umbilical cord blood CD4+ T cells." in: Leukemia, Vol. 22, Issue 12, pp. 2201-7, (2008) (PubMed).
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TGF-beta inhibits IL-2 production and promotes cell cycle arrest in TCR-activated effector/memory T cells in the presence of sustained TCR signal transduction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 3, pp. 1490-8, (2008) (PubMed).
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- Target
- IL-2 (IL2) (Interleukin 2 (IL2))
- Andere Bezeichnung
- IL-2 (IL2 Produkte)
- Synonyme
- IL2 antikoerper, IL-2 antikoerper, il2 antikoerper, TCGF antikoerper, lymphokine antikoerper, Il-2 antikoerper, POIL2 antikoerper, interleukin 2 antikoerper, interleukin-15 antikoerper, IL2 antikoerper, il2 antikoerper, LOC100303688 antikoerper, Il2 antikoerper
- Hintergrund
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Description: IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6 kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Aliases: Aldesleukin, TCGF, interleukin-2
- Molekulargewicht
- 17.6 kDa
- Gen-ID
- 3558
- HGNC
- 3558
- Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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