HPS1 Antikörper

Produktnummer ABIN969198

Produktdetails anti-HPS1 Antikörper

Target: HPS1 (Hermansky-Pudlak Syndrome 1 (HPS1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HPS1 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: HPS1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of HPS1 expressed in E. Coli.

Klon: 5G12G2

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-HPS1 Antikörper (ABIN969198)

Crowell, Gill: "Medical screening and evacuation: cauda equina syndrome in a combat zone." in: The Journal of orthopaedic and sports physical therapy, Vol. 39, Issue 7, pp. 541-9, (2009) (PubMed).

Fréchette, Leit, Woo, Lapointe, Jeannotte, Moradei, Paquin, Bouchain, Raeppel, Gaudette, Zhou, Vaisburg, Fournel, Yan, Trachy-Bourget, Kalita, Robert, Lu, Rahil, Robert Macleod, Besterman, Li, Delorme: "4-(Heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs as a novel class of histone deacetylase inhibitors." in: Bioorganic & medicinal chemistry letters, Vol. 18, Issue 4, pp. 1502-6, (2008) (PubMed).

Huizing, Parkes, Helip-Wooley, White, Gahl: "Platelet alpha granules in BLOC-2 and BLOC-3 subtypes of Hermansky-Pudlak syndrome." in: Platelets, Vol. 18, Issue 2, pp. 150-7, (2007) (PubMed).

Kobashi, Yoshida, Miyashita, Niki, Matsushima: "Hermansky-Pudlak syndrome with interstitial pneumonia without mutation of HSP1 gene." in: Internal medicine (Tokyo, Japan), Vol. 44, Issue 6, pp. 616-21, (2005) (PubMed).

Nazarian, Falcón-Pérez, DellAngelica: "Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8770-5, (2003) (PubMed).

Details zu HPS1

Target: HPS1 (Hermansky-Pudlak Syndrome 1 (HPS1))

Andere Bezeichnung: HPS1 (HPS1 Produkte)

Hintergrund:

Description: Hermansky-Pudlak syndrome 1. This protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Multiple transcript variants encoding distinct isoforms have been identified for this gene, the full-length sequences of some of these have not been determined yet.

Aliases: HPS, MGC5277, HPS1

Gen-ID: 3257

HGNC: 3257

UniProt: Q92902