HCK Antikörper

Produktnummer ABIN969187

Dieses Maus Monoklonal-Antikörper erkennt spezifisch HCK in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für HCK Antikörper (ABIN969187)

Target: HCK (Hemopoietic Cell Kinase (HCK))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HCK Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Klon: 3D12E10

Produktdetails anti-HCK Antikörper

Verwendungszweck: HCK Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of HCK expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-HCK Antikörper (ABIN969187)

Schnoor: "What I learned in Europe...." in: Environmental science & technology, Vol. 41, Issue 3, pp. 667, (2007) (PubMed).

Selimoglu, Ertekin, Altinkaynak: "Hyper-CK-emia in pediatric celiac disease: prevalence and clinical importance." in: Journal of clinical gastroenterology, Vol. 41, Issue 7, pp. 667-70, (2007) (PubMed).

Details zu HCK

Target: HCK (Hemopoietic Cell Kinase (HCK))

Andere Bezeichnung: HCK

Hintergrund: Hemopoietic cell kinase.The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling