FOXP2 Antikörper

Produktnummer ABIN969154

Dieses Maus Monoklonal-Antikörper erkennt spezifisch FOXP2 in ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für FOXP2 Antikörper (ABIN969154)

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOXP2 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 5C11A8

Produktdetails anti-FOXP2 Antikörper

Verwendungszweck: FOXP2 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human MAPK3 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-FOXP2 Antikörper (ABIN969154)

Konopka, Bomar, Winden, Coppola, Jonsson, Gao, Peng, Preuss, Wohlschlegel, Geschwind: "Human-specific transcriptional regulation of CNS development genes by FOXP2." in: Nature, Vol. 462, Issue 7270, pp. 213-7, (2009) (PubMed).

Ptak, Enard, Wiebe, Hellmann, Krause, Lachmann, Pääbo: "Linkage disequilibrium extends across putative selected sites in FOXP2." in: Molecular biology and evolution, Vol. 26, Issue 10, pp. 2181-4, (2009) (PubMed).

Details zu FOXP2

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Andere Bezeichnung: FOXP2

Hintergrund: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Molekulargewicht: 85 kDa

Gen-ID: 93986

UniProt: O15409