FOXP2 Antikörper (N-Term)

Produktnummer ABIN2778104

Der Kaninchen Polyklonal anti-FOXP2 Antikörper wird verwendet zum Nachweis von FOXP2 in Proben von Human, Maus, Ratte, Hund, Schwein, Kaninchen, Pferd, Ziege und Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC.

Kurzübersicht für FOXP2 Antikörper (N-Term) (ABIN2778104)

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Pferd, Ziege, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FOXP2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FOXP2 Antibody - N-terminal region

Sequenz: SGLKSPKSSD KQRPLQVPVS VAMMTPQVIT PQQMQQILQQ QVLSPQQLQA

Spezifität: Isoform 4 and 5

Homologie: Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33750-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FOXP2

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Andere Bezeichnung: FOXP2

Hintergrund:

Background Information: FOXP2 is an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Four alternative transcripts encoding three different isoforms have been identified.

Gene Name: Forkhead box P2

Alternative Symbols: SPCH1, CAGH44, TNRC10

Protein Name: Forkhead box protein P2

Molekulargewicht: 80kDa

Gen-ID: 93986

NCBI Accession: NP_055306

UniProt: O15409