c-FOS Antikörper
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- Target Alle c-FOS (c-Fos) Antikörper anzeigen
- c-FOS (c-Fos) (c-Fos)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser c-FOS Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Verwendungszweck
- FOS Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human FOS expressed in E. Coli.
- Klon
- 2G2
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1." in: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 53-63, (2010) (PubMed).
: "FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis." in: Cancer investigation, Vol. 27, Issue 8, pp. 816-24, (2009) (PubMed).
: "
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c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1." in: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 53-63, (2010) (PubMed).
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- Target
- c-FOS (c-Fos) (c-Fos)
- Andere Bezeichnung
- FOS (c-Fos Produkte)
- Hintergrund
- The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
- Molekulargewicht
- 40.7 kDa
- Gen-ID
- 2353
- UniProt
- P01100
- Pathways
- S100 Proteine
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