c-FOS Antikörper (AA 211-380)

Produktnummer ABIN3020748

Produktdetails anti-c-FOS Antikörper

Target: c-FOS (c-Fos) (c-Fos)

Bindungsspezifität: AA 211-380

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser c-FOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Sequenz: GFPEEMSVAS LDLTGGLPEV ATPESEEAFT LPLLNDPEPK PSVEPVKSIS SMELKTEPFD DFLFPASSRP SGSETARSVP DMDLSGSFYA ADWEPLHSGS LGMGPMATEL EPLCTPVVTC TPSCTAYTSS FVFTYPEADS FPSCAAAHRK GSSSNEPSSD SLSSPTLLAL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 211-380 of human c-Fos (NP_005243.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-c-FOS Antikörper (ABIN3020748)

Liu, Lai, Ma, Ke, Zhang, Liu, Zhang, Pei, Li, Yi, Shu, Shang, Liang, Huang: "CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression." in: Nature communications, Vol. 8, Issue 1, pp. 355, (2017) (PubMed).

Details zu c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Andere Bezeichnung: FOS (c-Fos Produkte)

Synonyme: AP-1 antikoerper, C-FOS antikoerper, p55 antikoerper, c-fos antikoerper, D12Rfj1 antikoerper, cFos antikoerper, cFOS antikoerper, fos antikoerper, Fos proto-oncogene, AP-1 transcription factor subunit antikoerper, FBJ osteosarcoma oncogene antikoerper, proto-oncogene c-Fos-like antikoerper, FOS antikoerper, Fos antikoerper, LOC101078177 antikoerper

Hintergrund: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.,FOS,AP-1,C-FOS,p55,c-Fos,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor biomarkers,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Neuroscience,Cell Type Marker,Neuron marker,FOS

Molekulargewicht: 28 kDa/36 kDa/40 kDa

Gen-ID: 2353

UniProt: P01100

Pathways: S100 Proteine