FLT1 Antikörper

Produktnummer ABIN969146

Der Maus Monoklonal Anti-FLT1-Antikörper wurde für ELISA validiert. Er ist geeignet, FLT1 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für FLT1 Antikörper (ABIN969146)

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FLT1 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 3D10

Produktdetails anti-FLT1 Antikörper

Verwendungszweck: FLT1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-FLT1 Antikörper (ABIN969146)

Man, Yang, Cai, Yao, Zheng: "Immunolocalization and expression of vascular endothelial growth factor receptors (VEGFRs) and neuropilins (NRPs) on keratinocytes in human epidermis." in: Molecular medicine (Cambridge, Mass.), Vol. 12, Issue 7-8, pp. 127-36, (2006) (PubMed).

Flick, Sapi, Perrotta, Maher, Halaban, Carter, Kacinski: "Recognition of activated CSF-1 receptor in breast carcinomas by a tyrosine 723 phosphospecific antibody." in: Oncogene, Vol. 14, Issue 21, pp. 2553-61, (1997) (PubMed).

Details zu FLT1

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Andere Bezeichnung: FLT1

Hintergrund: Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), also known as FLT1 or VEGFR-1. It is a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Molekulargewicht: 100 kDa

Gen-ID: 2321

UniProt: P17948

Pathways: RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals