FGG Antikörper

Produktnummer ABIN969142

Dieses Maus Monoklonal-Antikörper erkennt spezifisch FGG in IHC, ICC, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für FGG Antikörper (ABIN969142)

Target: FGG (Fibrinogen gamma Chain (FGG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGG Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA, Flow Cytometry (FACS)

Klon: 4H9

Produktdetails anti-FGG Antikörper

Verwendungszweck: FGG Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human FGG expressed in E. Coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-FGG Antikörper (ABIN969142)

Uitte de Willige, Standeven, Philippou, Ariëns: "The pleiotropic role of the fibrinogen gamma' chain in hemostasis." in: Blood, Vol. 114, Issue 19, pp. 3994-4001, (2009) (PubMed).

Bowley, Okumura, Lord: "Impaired protofibril formation in fibrinogen gamma N308K is due to altered D:D and "A:a" interactions." in: Biochemistry, Vol. 48, Issue 36, pp. 8656-63, (2009) (PubMed).

Details zu FGG

Target: FGG (Fibrinogen gamma Chain (FGG))

Andere Bezeichnung: FGG

Hintergrund: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Molekulargewicht: 52 kDa

Gen-ID: 2266

UniProt: P02679