FGG Antikörper

Produktnummer ABIN969141

Produktdetails anti-FGG Antikörper

Target: FGG (Fibrinogen gamma Chain (FGG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human FGG expressed in E. coli.

Klon: 5A6

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-FGG Antikörper (ABIN969141)

Uitte de Willige, Standeven, Philippou, Ariëns: "The pleiotropic role of the fibrinogen gamma' chain in hemostasis." in: Blood, Vol. 114, Issue 19, pp. 3994-4001, (2009) (PubMed).

Bowley, Okumura, Lord: "Impaired protofibril formation in fibrinogen gamma N308K is due to altered D:D and "A:a" interactions." in: Biochemistry, Vol. 48, Issue 36, pp. 8656-63, (2009) (PubMed).

Details zu FGG

Target: FGG (Fibrinogen gamma Chain (FGG))

Andere Bezeichnung: FGG (FGG Produkte)

Synonyme: FXII antikoerper, HAF antikoerper, 3010002H13Rik antikoerper, AI256424 antikoerper, fibrinogen antikoerper, FGG antikoerper, LOC100220680 antikoerper, fb60h05 antikoerper, fb62e01 antikoerper, wu:fb60h05 antikoerper, wu:fb62e01 antikoerper, zgc:56023 antikoerper, fibrinogen gamma chain antikoerper, coagulation factor XII (Hageman factor) antikoerper, fibrinogen gamma chain L homeolog antikoerper, FGG antikoerper, F12 antikoerper, fgg antikoerper, Fgg antikoerper, fgg.L antikoerper, CpipJ_CPIJ006387 antikoerper, CpipJ_CPIJ010087 antikoerper

Hintergrund:

Description: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.

Aliases: FGG

Molekulargewicht: 52 kDa

Gen-ID: 2266

HGNC: 2266