Fibrinogen beta Chain Antikörper (AA 30-300)

Produktnummer ABIN969136

Dieser Maus Monoklonal Antikörper detektiert spezifisch Fibrinogen beta Chain in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für Fibrinogen beta Chain Antikörper (AA 30-300) (ABIN969136)

Target: Fibrinogen beta Chain (FGB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 1F9

Produktdetails anti-Fibrinogen beta Chain Antikörper

Bindungsspezifität: AA 30-300

Verwendungszweck: FGB Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human FGB (aa30-300) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Fibrinogen beta Chain Antikörper (ABIN969136)

Koch, Hoppmann, Biele, Mueller, Schömig, Kastrati: "Fibrinogen genes and myocardial infarction: a haplotype analysis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 4, pp. 758-63, (2008) (PubMed).

Vu, Bolton-Maggs, Parr, Morris, de Moerloose, Neerman-Arbez: "Congenital afibrinogenemia: identification and expression of a missense mutation in FGB impairing fibrinogen secretion." in: Blood, Vol. 102, Issue 13, pp. 4413-5, (2003) (PubMed).

Details zu Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Andere Bezeichnung: FGB

Hintergrund: Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

Molekulargewicht: 52 kDa

Gen-ID: 2244

UniProt: P02675