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Fibrinogen beta Chain Antikörper (AA 30-300)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Fibrinogen beta Chain in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN969136

Kurzübersicht für Fibrinogen beta Chain Antikörper (AA 30-300) (ABIN969136)

Target

Alle Fibrinogen beta Chain (FGB) Antikörper anzeigen
Fibrinogen beta Chain (FGB)

Reaktivität

  • 81
  • 18
  • 18
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 80
  • 25
  • 1
Maus

Klonalität

  • 72
  • 34
Monoklonal

Konjugat

  • 66
  • 16
  • 10
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert

Applikation

  • 79
  • 53
  • 36
  • 24
  • 16
  • 16
  • 10
  • 8
  • 7
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA

Klon

1F9
  • Bindungsspezifität

    • 12
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-300

    Verwendungszweck

    FGB Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human FGB (aa30-300) expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Koch, Hoppmann, Biele, Mueller, Schömig, Kastrati: "Fibrinogen genes and myocardial infarction: a haplotype analysis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 4, pp. 758-63, (2008) (PubMed).

    Vu, Bolton-Maggs, Parr, Morris, de Moerloose, Neerman-Arbez: "Congenital afibrinogenemia: identification and expression of a missense mutation in FGB impairing fibrinogen secretion." in: Blood, Vol. 102, Issue 13, pp. 4413-5, (2003) (PubMed).

  • Target

    Fibrinogen beta Chain (FGB)

    Andere Bezeichnung

    FGB

    Hintergrund

    Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.

    Molekulargewicht

    52 kDa

    Gen-ID

    2244

    UniProt

    P02675
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