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Fibrinogen beta Chain Antikörper (AA 30-300)
FGB
Reaktivität: Human
WB, ELISA
Wirt: Maus
Monoclonal
1F9
unconjugated
Produktdetails anti-Fibrinogen beta Chain Antikörper
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Target
Alle Fibrinogen beta Chain (FGB) Antikörper anzeigen
Fibrinogen beta Chain (FGB)
Bindungsspezifität
Alle Epitope für Fibrinogen beta Chain Antikörper
AA 30-300
Reaktivität
Alle Reaktivitäten für Fibrinogen beta Chain Antikörper
Human
Wirt
Alle Wirte für Fibrinogen beta Chain Antikörper
Maus
Klonalität
Alle Klonalitäten für Fibrinogen beta Chain Antikörper
Monoklonal
Konjugat
Alle Konjugate für Fibrinogen beta Chain Antikörper
Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Fibrinogen beta Chain Antikörper
Western Blotting (WB), ELISA
Verwendungszweck
FGB Antibody
Aufreinigung
Ascitic fluid
Immunogen
Purified recombinant fragment of human FGB (aa30-300) expressed in E. Coli.
Klon
1F9
Isotyp
IgG1
Top Product
Discover our top product FGB Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Referenzen für anti-Fibrinogen beta Chain Antikörper (ABIN969136)
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Koch, Hoppmann, Biele, Mueller, Schömig, Kastrati : "Fibrinogen genes and myocardial infarction: a haplotype analysis. " in: Arteriosclerosis, thrombosis, and vascular biology , Vol. 28 , Issue 4 , pp. 758-63 , (2008 ) (PubMed ).
Vu, Bolton-Maggs, Parr, Morris, de Moerloose, Neerman-Arbez : "Congenital afibrinogenemia: identification and expression of a missense mutation in FGB impairing fibrinogen secretion. " in: Blood , Vol. 102 , Issue 13 , pp. 4413-5 , (2003 ) (PubMed ).
Details zu Fibrinogen beta Chain
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Target
Fibrinogen beta Chain (FGB)
Andere Bezeichnung
FGB (FGB Produkte )
Hintergrund
Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Molekulargewicht
52 kDa
Gen-ID
2244
UniProt
P02675
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