EPO Antikörper

Produktnummer ABIN969109

Dieses Maus Monoklonal-Antikörper erkennt spezifisch EPO in WB, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für EPO Antikörper (ABIN969109)

Target: EPO (Erythropoietin (EPO))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Klon: 4F11

Produktdetails anti-EPO Antikörper

Verwendungszweck: EPO Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human EPO expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-EPO Antikörper (ABIN969109)

Hirschler-Laszkiewicz, Tong, Conrad, Zhang, Flint, Barber, Barber, Cheung, Miller: "TRPC3 activation by erythropoietin is modulated by TRPC6." in: The Journal of biological chemistry, Vol. 284, Issue 7, pp. 4567-81, (2009) (PubMed).

Details zu EPO

Target: EPO (Erythropoietin (EPO))

Andere Bezeichnung: EPO

Substanzklasse: Hormone

Hintergrund: Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.Tissue specificity: Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.

Molekulargewicht: 21 kDa

UniProt: P01588

Pathways: JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity