Dieses Anti-EPH Receptor A8-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von EPH Receptor A8 in ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Gu, Shim, Shin, Kim, Park, Han, Park: "The EphA8 receptor induces sustained MAP kinase activation to promote neurite outgrowth in neuronal cells." in: Oncogene, Vol. 24, Issue 26, pp. 4243-56, (2005) (PubMed).
Yamaguchi, Pasquale: "Eph receptors in the adult brain." in: Current opinion in neurobiology, Vol. 14, Issue 3, pp. 288-96, (2004) (PubMed).
Target
EPH Receptor A8 (EPHA8)
Andere Bezeichnung
EphA8
Hintergrund
EphA8: EPH receptor A8. This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.