Der Maus Monoklonal Anti-EPH Receptor A3-Antikörper wurde für ELISA validiert. Er ist geeignet, EPH Receptor A3 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
EPHA3
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Janes, Saha, Barton, Kolev, Wimmer-Kleikamp, Nievergall, Blobel, Himanen, Lackmann, Nikolov: "Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans." in: Cell, Vol. 123, Issue 2, pp. 291-304, (2005) (PubMed).
Target
EPH Receptor A3 (EPHA3)
Andere Bezeichnung
EphA3
Hintergrund
EphA3: EPH receptor A3. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.