Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CD38 Antikörper

Der Maus Monoklonal Anti-CD38-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, CD38 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.
Produktnummer ABIN969023

Kurzübersicht für CD38 Antikörper (ABIN969023)

Target

Alle CD38 Antikörper anzeigen
CD38

Reaktivität

  • 190
  • 74
  • 29
  • 12
  • 12
  • 12
  • 2
  • 1
  • 1
Human

Wirt

  • 117
  • 110
  • 34
  • 1
  • 1
  • 1
  • 1
Maus

Klonalität

  • 179
  • 84
  • 1
Monoklonal

Konjugat

  • 105
  • 16
  • 16
  • 13
  • 12
  • 6
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD38 Antikörper ist unkonjugiert

Applikation

  • 178
  • 89
  • 72
  • 46
  • 42
  • 37
  • 30
  • 26
  • 26
  • 17
  • 14
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), ELISA

Klon

6E12D4A12
  • Verwendungszweck

    CD38 Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human CD38 expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Pavón, Muñoz, Navarro, Raya-Alvarez, Callejas-Rubio, Navarro-Pelayo, Ortego-Centeno, Sancho, Zubiaur: "Increased association of CD38 with lipid rafts in T cells from patients with systemic lupus erythematosus and in activated normal T cells." in: Molecular immunology, Vol. 43, Issue 7, pp. 1029-39, (2005) (PubMed).

    Liu, Verfaillie: "Myeloid-lymphoid initiating cells (ML-IC) are highly enriched in the rhodamine-c-kit(+)CD33(-)CD38(-) fraction of umbilical cord CD34(+) cells." in: Experimental hematology, Vol. 30, Issue 6, pp. 582-9, (2002) (PubMed).

  • Target

    CD38

    Hintergrund

    CD38 is a type II integral membrane glycoprotein which is present on early B and T cell lineages and activated B and T cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B cells, mitogen-activated T cells, monocytes and Ig-secreting plasma cells. CD38 acts as a NAD glycohydrolase in T lym- phocytes. On hematopoietic cells CD38 induces activation, proliferation, and differentiation of mature T and B cells and mediates apoptosis of myeloid and lymphoid progenitor cells. In addition to acting as a signaling receptor, CD38 is also an enzyme capable of producing several calcium-mobilizing metabo- lites, including cyclic adenosine diphosphate ribose (cADPR). CD38 also plays a role in maintaining survival of an invariant NK T (iNKT) cell subset that preferentially contributes to the maintenance of immunological tolerance.

    Molekulargewicht

    34 kDa

    Gen-ID

    952

    UniProt

    P28907
Sie sind hier:
Chat with us!