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APOB Antikörper

Dieses Anti-APOB-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von APOB in ELISA, ICC und FACS. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Produktnummer ABIN968961

Kurzübersicht für APOB Antikörper (ABIN968961)

Target

Alle APOB Antikörper anzeigen
APOB (Apolipoprotein B (APOB))

Reaktivität

  • 127
  • 35
  • 34
  • 10
  • 3
Human

Wirt

  • 91
  • 67
  • 14
  • 2
  • 2
Maus

Klonalität

  • 98
  • 76
Monoklonal

Konjugat

  • 92
  • 27
  • 21
  • 7
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser APOB Antikörper ist unkonjugiert

Applikation

  • 113
  • 81
  • 63
  • 45
  • 43
  • 18
  • 16
  • 14
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon

6G6
  • Verwendungszweck

    ApoB Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of human ApoB expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Benn: "Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." in: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, (2009) (PubMed).

    Peterson, Mack, Hall, Alsup, Alexander, Sully, Sawires, Cheung, Otto, Gresham: "Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection." in: Cell host & microbe, Vol. 4, Issue 6, pp. 555-66, (2008) (PubMed).

  • Target

    APOB (Apolipoprotein B (APOB))

    Andere Bezeichnung

    ApoB

    Hintergrund

    This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

    Molekulargewicht

    516 kDa

    Gen-ID

    338

    UniProt

    P04114

    Pathways

    Lipid Metabolism
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