Smooth Muscle Actin Antikörper
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- Target Alle Smooth Muscle Actin (ACTA2) Antikörper anzeigen
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Smooth Muscle Actin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
- Verwendungszweck
- ACTA2 Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Synthesized peptide of human ACTA2.
- Klon
- 4A4
- Isotyp
- IgG1
- Top Product
- Discover our top product ACTA2 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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ACTA2 is not a major disease-causing gene for moyamoya disease." in: Journal of human genetics, Vol. 54, Issue 11, pp. 687-8, (2009) (PubMed).
: "Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD)." in: Human mutation, Vol. 30, Issue 10, pp. 1406-11, (2009) (PubMed).
: "
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ACTA2 is not a major disease-causing gene for moyamoya disease." in: Journal of human genetics, Vol. 54, Issue 11, pp. 687-8, (2009) (PubMed).
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- Target
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
- Andere Bezeichnung
- ACTA2 (ACTA2 Produkte)
- Hintergrund
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Description: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Aliases: AAT6, ACTSA, α-Smooth Muscle Actin
- Molekulargewicht
- 42kDa
- Gen-ID
- 59
- HGNC
- 59
- UniProt
- P62736
- Pathways
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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