ABL2 Antikörper
(2 Referenzen)-
- Target Alle ABL2 Antikörper anzeigen
- ABL2
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ABL2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of ABL2 expressed in E. coli.
- Klon
- 1H1
- Isotyp
- IgG1
- Top Product
- Discover our top product ABL2 Primärantikörper
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anti-ABL2 (ABL2) (AA 743-842) antibody
ABL2 Reaktivität: Human WB, ELISA, PLA, RNAi Wirt: Maus Monoclonal 6D5 unconjugated
anti-ABL2 (ABL2) (AA 743-842) antibodyABL2 Reaktivität: Human WB, ELISA, IHC (p), IF Wirt: Maus Monoclonal 5C6 unconjugated
anti-ABL2 (ABL2) antibodyABL2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-ABL2 (ABL2) (pTyr393), (pTyr439) antibodyABL2 Reaktivität: Human WB, IHC (p), DB Wirt: Kaninchen Polyclonal RB7532 unconjugated
anti-ABL2 (ABL2) (AA 1011-1044), (C-Term) antibodyABL2 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB50829 unconjugated
anti-ABL2 (ABL2) (AA 862-1064) antibodyABL2 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-ABL2 (ABL2) (AA 417-446) antibodyABL2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB7532 unconjugated
anti-ABL2 (ABL2) antibodyABL2 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-ABL2 (ABL2) antibodyABL2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Maus Monoclonal 2C3 unconjugated
anti-ABL2 (ABL2) (Center) antibodyABL2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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: "Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease." in: Oncogene, Vol. 21, Issue 21, pp. 3314-33, (2002) (PubMed).
: "A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation." in: Blood, Vol. 95, Issue 6, pp. 2126-31, (2000) (PubMed).
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: "Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease." in: Oncogene, Vol. 21, Issue 21, pp. 3314-33, (2002) (PubMed).
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- Target
- ABL2
- Andere Bezeichnung
- ABL2 (ABL2 Produkte)
- Hintergrund
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Description: ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases. ABL2 and c-Abl share 89 % , 90 and 93 % identity in their SH3, SH2 and tyrosine domain, but only 29 % identity in the carboxy-terminal half. The human c-Abl and ABL2 genes are expressed ubiquitously. ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization. c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML). The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons.
Aliases: ARG, ABLL, FLJ22224, FLJ31718, FLJ41441
- Molekulargewicht
- 128 kDa
- Gen-ID
- 27
- HGNC
- 27
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