RAB11A Antikörper (AA 86-207)

Produktnummer ABIN968091

Dieses Anti-RAB11A-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von RAB11A in WB, IHC und IP. Geeignet für Human, Maus, Ratte, Hund und Huhn. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für RAB11A Antikörper (AA 86-207) (ABIN968091)

Target: RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

Reaktivität: Human, Maus, Ratte, Hund, Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAB11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: 47-Rab11

Produktdetails anti-RAB11A Antikörper

Bindungsspezifität: AA 86-207

Kreuzreaktivität: Hund, Huhn, Maus, Ratte (Rattus)

Produktmerkmale: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Human Rab11 aa. 86-207

Isotyp: IgG2a

Anwendungsinformationen

Kommentare:

Related Products: ABIN968619, ABIN967389

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store undiluted at -20°C.

Referenzen für anti-RAB11A Antikörper (ABIN968091)

Steiner, Sarria, Glauser, Magnin, Catsicas, Hirling: "Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD." in: The Journal of cell biology, Vol. 157, Issue 7, pp. 1197-209, (2002) (PubMed).

Choudhury, Dominguez, Puri, Sharma, Narita, Wheatley, Marks, Pagano: "Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells." in: The Journal of clinical investigation, Vol. 109, Issue 12, pp. 1541-50, (2002) (PubMed).

Woods, Roberts, Choudhary, Barry, Mazaki, Sabe, Morley, Critchley, Norman: "Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells." in: The Journal of biological chemistry, Vol. 277, Issue 8, pp. 6428-37, (2002) (PubMed).

Lai, Stubbs, Artzt: "Molecular analysis of mouse Rab11b: a new type of mammalian YPT/Rab protein." in: Genomics, Vol. 22, Issue 3, pp. 610-6, (1995) (PubMed).

Sakurada, Uchida, Yamaguchi, Aisaka, Ito, Ohmori, Takeyama, Ueda, Hori, Ohyanagi: "Molecular cloning and characterization of a ras p21-like GTP-binding protein (24KG) from rat liver." in: Biochemical and biophysical research communications, Vol. 177, Issue 3, pp. 1224-32, (1991) (PubMed).

Details zu RAB11A

Target: RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

Andere Bezeichnung: Rab11

Hintergrund: The Rab proteins are small GTP-binding molecules that are localized to specific intracellular vesicles and organelles. It has been proposed that Rab proteins cycle between GTP- and GDP-bound forms and that this is related to their function as regulators of vesicular traffic. The Rab11 gene encodes a 24 kDa protein of 214 amino acids that has been detected in liver, brain, testis, spleen, and heart. Rab11 protein was isolated from the golgi-microsomal fraction of rat liver and has been detected in the Trans-golgi Network, secretory vesicles, and the pericentriolar recycling endosomes. The distribution of Rab11 indicates that this small protein is involved in regulating traffic at the Golgi complex.

Molekulargewicht: 24 kDa

Pathways: Regulation of Cell Size, Thromboxane A2 Receptor Signaling, Regulation of long-term Neuronal Synaptic Plasticity