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TEK Antikörper (Extracellular Domain)

TEK Reaktivität: Human, Maus WB, IHC (fro) Wirt: Maus Monoclonal 33 unconjugated
Produktnummer ABIN967565
  • Target Alle TEK Antikörper anzeigen
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Bindungsspezifität
    • 20
    • 19
    • 16
    • 11
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    Reaktivität
    • 144
    • 74
    • 49
    • 22
    • 4
    • 3
    Human, Maus
    Wirt
    • 128
    • 25
    • 6
    • 3
    • 2
    Maus
    Klonalität
    • 134
    • 30
    Monoklonal
    Konjugat
    • 71
    • 12
    • 9
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TEK Antikörper ist unkonjugiert
    Applikation
    • 81
    • 60
    • 40
    • 40
    • 38
    • 33
    • 14
    • 13
    • 12
    • 8
    • 8
    • 8
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Marke
    BD Pharmingen™
    Kreuzreaktivität
    Maus
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    3. Please refer to us for technical protocols.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human TIE2 extracellular domain Recombinant Protein
    Klon
    33
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product TEK Primärantikörper
  • Kommentare

    Related Products: ABIN967389, ABIN968537

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Partanen, Dumont: "Functions of Tie1 and Tie2 receptor tyrosine kinases in vascular development." in: Current topics in microbiology and immunology, Vol. 237, Issue 4, pp. 159-72, (1999) (PubMed).

    Peters, Coogan, Berry, Marks, Iglehart, Kontos, Rao, Sankar, Trogan: "Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis." in: British journal of cancer, Vol. 77, Issue 1, pp. 51-6, (1998) (PubMed).

    Wong, Haroon, Werner, Dewhirst, Greenberg, Peters: "Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues." in: Circulation research, Vol. 81, Issue 4, pp. 567-74, (1997) (PubMed).

    Dumont, Gradwohl, Fong, Puri, Gertsenstein, Auerbach, Breitman: "Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo." in: Genes & development, Vol. 8, Issue 16, pp. 1897-909, (1994) (PubMed).

  • Target
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Andere Bezeichnung
    TIE2 (TEK Produkte)
    Synonyme
    TEK antikoerper, DKFZp469E064 antikoerper, AA517024 antikoerper, Cd202b antikoerper, Hyk antikoerper, Tie2 antikoerper, tie-2 antikoerper, CD202B antikoerper, TIE-2 antikoerper, TIE2 antikoerper, VMCM antikoerper, VMCM1 antikoerper, Tie-2 antikoerper, tie2 antikoerper, TEK receptor tyrosine kinase antikoerper, angiopoietin-1 receptor antikoerper, TEK tyrosine kinase, endothelial antikoerper, TEK antikoerper, LOC100408334 antikoerper, tek antikoerper, Tek antikoerper
    Hintergrund
    The TIE receptor family is a member of the class of receptors called the receptor tyrosine kinases (RKT). RKTs are cell surface receptors which also contain a protein kinase domain in their intracellular portion and upon binding of their specific growth factor, initiate a series of downstream biological events. TIE receptors, designated Tie1 and Tie2 (Tek) have a tissue distribution which is limited primarily to cells of endothelial origin. Tie2 has been shown to be required for the normal development of vascular structures during embryogenesis. It has also been demonstrated to play a role in normal and pathological angiogenesis in adults. Tie2 has a predicted molecular weight of 126 kD, but may be observable at ~130-165 kDa. This antibody has been reported to recognize human and mouse Tie2 but not Tie1.
    Molekulargewicht
    130-165 kDa
    Pathways
    RTK Signalweg, Growth Factor Binding
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