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Transferrin Receptor Antikörper

Name: Transferrin Receptor Antikörper
Brand: antibodies-online
SKU: ABIN967201
Price: 363 EUR
Availability: InStock

TFRC Reaktivität: Human FACS, IHC (fro) Wirt: Maus Monoclonal B349(DF1513) unconjugated

(2 Referenzen)

Produktnummer ABIN967201

Datenblatt (PDF)

Target Alle Transferrin Receptor (TFRC) Antikörper anzeigen

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
Reaktivität
211

96

35

7

6

4

4

4

4

2

2

2

1
Human
Wirt
127

114

37

1

1

1
Maus
Passende Sekundärantikörper
Klonalität
180

97

3
Monoklonal
Konjugat
132

27

24

17

11

5

4

4

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Transferrin Receptor Antikörper ist unkonjugiert
Applikation
168

137

74

69

59

44

26

26

21

12

7

6

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität

This antibody reacts with the transferrin receptor, a 180-190 kD transmembrane glycoprotein which exists as a 95 kD homodimer with interchain disulfide bond. The specificity of these antibodies, as demonstrated by immunoprecipitation, are equivalent to OKT9, B3/25 and BerT9.

Aufreinigung

Purified.

Immunogen

Cell line KG1.

Klon

B349(DF1513)

Isotyp

IgG1 kappa

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TFRC Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Immunofluorescense 10-20 micrograms/ml.
Flow cytometry: 1 micrograms/10^6 cells.
Immunohistochemistry: (Acetone-fixed frozen) 5-15 micrograms/mL using avidin-biotin system. This antibody is an indicator of proliferation activity. It also has prognostic significance when typing tumors, such as leukemias and lymphomas.
Staining Procedure: This antibody can be used on frozen tissue sections only in IHC.

Kommentare

Cellular Localization: Cell membrane.
Recommended Positive Control: Tonsil

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.4 mg/ml.

Buffer

0.2 mg Immunoglobulin in cell culture supernatant, 50 mM Sodium Borate, 150 mM Sodium Chloride, pH 8.0

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C
Friden, Walus, Musso, Taylor, Malfroy, Starzyk: "Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4771-5, (1991) (PubMed).

Jing, Spencer, Miller, Hopkins, Trowbridge: "Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization." in: The Journal of cell biology, Vol. 110, Issue 2, pp. 283-94, (1990) (PubMed).
Target

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung

Transferrin Receptor,CD71 (TFRC Produkte)

Molekulargewicht

~9095 kDa

Gen-ID

7037

Pathways

Transition Metal Ion Homeostasis