Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Reticulon 3 Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Reticulon 3 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.
Produktnummer ABIN966979

Kurzübersicht für Reticulon 3 Antikörper (ABIN966979)

Target

Alle Reticulon 3 (RTN3) Antikörper anzeigen
Reticulon 3 (RTN3)

Reaktivität

  • 16
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 11
  • 5
Maus

Klonalität

  • 13
  • 3
Monoklonal

Konjugat

  • 16
Dieser Reticulon 3 Antikörper ist unkonjugiert

Applikation

  • 12
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

Klon

1E11
  • Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of RTN3 expressed in E. Coli.

    Isotyp

    IgG2a
  • Applikationshinweise

    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C
  • Wakana, Koyama, Nakajima, Hatsuzawa, Nagahama, Tani, Hauri, Melançon, Tagaya: "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi." in: Biochemical and biophysical research communications, Vol. 334, Issue 4, pp. 1198-205, (2005) (PubMed).

    Brain, Wilson, Johnson, Sanderson, Bestari, Hanson, Sibley, Solomon: "Effects of a mixture of tetracyclines to Lemna gibba and Myriophyllum sibiricum evaluated in aquatic microcosms." in: Environmental pollution (Barking, Essex : 1987), Vol. 138, Issue 3, pp. 425-42, (2005) (PubMed).

    Cai, Saiyin, Lin, Zhang, Tang, Pan, Yu: "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain." in: Brain research. Molecular brain research, Vol. 138, Issue 2, pp. 236-43, (2005) (PubMed).

    Oertle, Klinger, Stuermer, Schwab: "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 10, pp. 1238-47, (2003) (PubMed).

  • Target

    Reticulon 3 (RTN3)

    Andere Bezeichnung

    RTN3

    Hintergrund

    RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
    Synonyms: HAP, ASYIP, NSPL2, NSPLII, RTN3-A1

    Molekulargewicht

    113kDa

    Gen-ID

    10313
Sie sind hier:
Chat with us!