PPARG Antikörper

Produktnummer ABIN966887

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Monoklonal anti-PPARG Antikörper wird verwendet zum Nachweis von PPARG in Proben von Human. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für PPARG Antikörper (ABIN966887)

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Monoklonal

Konjugat: Dieser PPARG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PPARG Antikörper

Spezifität: Ni-NTA purified truncated recombinant PPARG expressed in E. Coli strain BL21 (DE3)

Aufreinigung: Crude ascites.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
IF : 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Referenzen für anti-PPARG Antikörper (ABIN966887)

Yang, Ma, Ma, Fogo: "Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis." in: Kidney international, Vol. 69, Issue 10, pp. 1756-64, (2006) (PubMed).

Weng, Chen, Pinzone, Ringel, Chen: "Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones." in: Endocrine-related cancer, Vol. 13, Issue 2, pp. 401-13, (2006) (PubMed).

Ahdjoudj, Kaabeche, Holy, Fromigué, Modrowski, Zérath, Marie: "Transforming growth factor-beta inhibits CCAAT/enhancer-binding protein expression and PPARgamma activity in unloaded bone marrow stromal cells." in: Experimental cell research, Vol. 303, Issue 1, pp. 138-47, (2004) (PubMed).

Details zu PPARG

Target: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Andere Bezeichnung: PPARG

Hintergrund: PPAR gamma(PPARG), which encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. Three subtypes of PPARs are known: PPAR-alpha, PPARdelta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Gen-ID: 5468

Pathways: MAPK Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation