Progesterone Receptor Antikörper (AA 730-871)

Produktnummer ABIN966829

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Progesterone Receptor in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für Progesterone Receptor Antikörper (AA 730-871) (ABIN966829)

Target: Progesterone Receptor (PGR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Progesterone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 8A11H1

Produktdetails anti-Progesterone Receptor Antikörper

Bindungsspezifität: AA 730-871

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of PGR (aa730-871) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-Progesterone Receptor Antikörper (ABIN966829)

Polo, José Galindo, Martínez, Alvarez, Arévalo, Asensi, Cánoves, Cáncer, Collazos, Estrada, Gómez-Candela, Johnston, Locutura, López-Aldeguer, Lozano, Miralles, Muñoz-Sanz, Ortega, Pascua, Pedrol, Pulido, San Martín, Sanz, Viciana, Chamorro,: "[Recommendations of the Study Group for Metabolic Alterations/Secretariat for the National AIDS Plan (GEAM/SPNS) on the management of metabolic and morphologic alterations in patients with HIV infection]." in: Enfermedades infecciosas y microbiología clínica, Vol. 24, Issue 2, pp. 96-117, (2006) (PubMed).

Buser, Gass-Handel, Wyszomierski, Doppler, Leonhardt, Schaack, Rosen, Watkin, Anderson, Edwards: "Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 1, pp. 106-25, (2006) (PubMed).

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: PGR

Hintergrund: PGR: progesterone receptor. This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined.
Synonyms: PR, NR3C3, PGR

Gen-ID: 5241

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration